What are the Side Effects of Glutathione?

Glutathione IV Therapy

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What is glutathione, and why are so many people turning to it to improve their health? Does glutathione therapy cause any side effects? This article will answer these questions to help you make an informed decision about your health options.

Glutathione is a powerful antioxidant found in every cell of the body. This compound provides many natural benefits, such as supporting the immune system, improving sleep, reducing stress, fighting inflammation, and aiding liver function. Glutathione's anti-aging properties can reduce wrinkles and promote healthy, glowing skin. It helps combat fatty liver disease and supports cellular repair.

While glutathione benefits far outweigh any potential risk factors, certain risk factors may exist. Understanding these risk factors can help you and your medical provider decide whether glutathione IV therapy is right for you.

Why Use Glutathione Supplements?

Glutathione levels in the body decline with age. Low levels of glutathione are linked to conditions such as Parkinson’s disease and other neurodegenerative disorders. As the body’s ability to produce glutathione declines, supplementation becomes the only way to replenish this crucial antioxidant.

Oral and intravenous glutathione supplements are available; however, glutathione IV therapy is a more effective source of glutathione benefits than oral supplementation. Oral glutathione supplements have poor bioavailability, meaning the body lacks an efficient method of absorbing the compound for use.

On the other hand, glutathione IV therapy delivers the compound directly to the bloodstream, where it is quickly distributed throughout the body. IV therapy provides a faster and more efficient method of glutathione supplementation than pills or tablets.

How Does Glutathione Work?

Glutathione chemical

Glutathione is a tripeptide produced by the liver, consisting of γ-l-glutamyl-l-cysteinyl-glycine. Known as the master antioxidant, glutathione prevents damage caused by unstable atoms called free radicals. While these atoms serve some beneficial purposes, a free radical imbalance can cause a condition called oxidative stress, resulting in the degradation of proteins, fats, carbohydrates, and DNA. Oxidative stress from free radicals leads to cell damage and faster cellular degeneration, accelerating the aging process. Major diseases such as cancer and cardiovascular ailments can be associated with inflammation caused by oxidative stress.

Glutathione allows the body to counteract the harmful effects of free radicals while enabling other antioxidants, such as vitamins C and E, to join the combat. More antioxidants fighting free radicals should lead to healthier outcomes. 

What About Glutathione Side Effects?

Glutathione is generally well-tolerated, and adverse side effects of glutathione are relatively rare. Still, some people do experience side effects of glutathione, if only temporarily. Your body should adjust to glutathione treatment within a few days, but side effects can last longer in some individuals.

The most common side effects of glutathione include:

Allergic Reaction

Glutathione sensitivity can result in breathing problems, skin rashes, hives, and swelling of the mouth, tongue, and throat. Other allergic reactions may include paler skin and an irregular heartbeat.

Rarely, an allergic reaction to glutathione results in a person feeling extremely dizzy or even passing out.

Asthma Attacks

Asthma attacks are more likely when using an inhaled form of glutathione, not glutathione IV therapy. Since asthma is often caused by an allergic reaction, wheezing, tightness in the throat or chest, or breathing issues may indicate a glutathione sensitivity.

GI Issues, Bloating, and Cramps

Gastrointestinal issues, particularly bloating and cramps, may affect some glutathione users. These complaints occur most often in people taking high doses of glutathione and usually resolve within a few days.

Zinc Deficiency

Zinc is one of the most critical minerals in your body. It aids in wound healing, keeping the immune system strong, and building DNA and proteins. In the U.S., zinc deficiency is unusual, as most people receive sufficient zinc from foods as varied as meat, fish, fortified cereals, beans, eggs, nuts, and dairy products.

While short-term use of glutathione should not affect zinc levels, long-term use has been linked to zinc deficiency. Symptoms of zinc deficiency include:

  • Appetite loss
  • Diarrhea
  • Issues with sense of smell and taste
  • Lethargy
  • Slow wound healing
  • Open sores on the skin
  • Unintended weight loss

If you experience any zinc deficiency symptoms, make an appointment with your doctor for an examination and testing.

Reducing the Risks of Side Effects

While the side effects of glutathione IV therapy are usually mild, there are exceptions. Reduce the odds of side effects with glutathione IV therapy by taking the following steps:

Talk With Your Doctor

Discuss glutathione IV therapy with your doctor before starting a treatment regimen. This is especially crucial if you have a history of asthma.

Glutathione may interact with certain medications. Always tell your doctor about any medications you take, whether prescription or over-the-counter. While most glutathione medication interactions are mild, there is a risk that glutathione supplementation could lower a medication’s effectiveness. Your doctor will advise you about substituting drugs that may interact with glutathione.

Avoid Glutathione IV Therapy When Pregnant or Nursing

More research is needed to verify the safety of glutathione supplementation for women who are pregnant or breastfeeding.

Begin With a Lower Dosage

Starting your supplement schedule with a lower dosage and working your way up to the recommended dosage may help you avoid any potential side effects of glutathione.

Monitor Your Body’s Response

Pay close attention to how your body responds to glutathione IV therapy. Keep a record of any changes that may indicate an allergic reaction or a gastrointestinal problem, however mild.

Home IV Therapy

The most convenient way to receive glutathione IV therapy is in the comfort of your own home. A licensed nurse will arrive at your door quickly—usually within one hour of making the appointment—at any time of the day or night.

Our Services

Reset IV offers personal IV therapy 24 hours a day, seven days a week, with no travel fees. A typical IV therapy session takes between 30 and 45 minutes, depending on the package you choose. Your nurse will answer any questions you have.

Glutathione IV therapy is available on its own or as part of several of our IV packages, including those designed for workout support, sexual health, and skin rejuvenation. 

During your session, you can read, watch TV, listen to music, or just sit back and relax. Contact Reset IV today to find out what glutathione IV therapy can do for you!


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