Zofran for Hangovers: Benefits, Risks, and Alternatives

A bad hangover may last 24 hours or more. That’s basically 24 hours of misery. Fortunately, there are methods available for alleviating hangover symptoms promptly so you can feel like yourself again. When it comes to nausea and vomiting, taking Zofran after drinking can help.

While Zofran for hangovers offers various benefits, there are also risks involved. Learn more about Zofran for alcohol nausea and why IV therapy from Reset IV offers a better alternative option for alleviating your hangover discomfort as quickly as possible.

Zofran’s Role in Hangover Relief

Nausea and vomiting frequently accompany hangovers. Zofran, the brand name of ondansetron, is a strong antiemetic (preventing nausea and vomiting). A selective 5-HTC3 receptor antagonist, it is frequently prescribed to patients dealing with chemotherapy, as well as radiation or surgery. Zofran is available only by prescription. 

 Does Zofran help with nausea from drinking? The answer is yes but with a caveat.

First, it is necessary to know why too much alcohol consumption results in hangovers and symptoms such as nausea and vomiting. Drinking too much dehydrates the body. Because alcohol is a diuretic, it causes excessive urination. The body loses more fluids than it takes in, resulting in dehydration. Vital electrolytes are also lost.

Alcohol also irritates the stomach lining, resulting in nausea and vomiting. That’s where Zofran for hangovers comes in. 

How does Zofran help with a hangover? Zofran works by blocking serotonin receptors in the brain. Serotonin is known as the “feel good” hormone because it regulates mood. Most of the body’s serotonin is found in the digestive tract, where it aids in bowel function control. However, when serotonin is released into the gastrointestinal system more rapidly than digestion allows, the brain reacts by triggering nausea.

Limitations of Zofran in Treating Hangovers

Even though the drug is effective, there are contraindications relating to using Zofran for hangovers. Pregnant or breastfeeding women or those trying to get pregnant should not take Zofran–and it is also not a good idea for them to consume alcohol during this time. Those with any of the following conditions should not take Zofran unless cleared by a doctor:

  • Heart disease
  • Liver disease
  • Irregular heartbeat
  • Low magnesium or potassium levels

Certain medications may interact with Zofran. Let your medical team know about all of the medications or supplements you currently take. Some common medications that should not be taken with Zofran include:

  • Some antibiotics, such as Linezolid, generically known as Zyvox 
  • Fungal infection drugs, including fluconazole, itraconazole, ketoconazole, posaconazole, and voriconazole.
  • Tramadol
  • Triptan, a migraine medication

Because some antidepressants and antianxiety medications may interact with Zofran, provide your medical team with the name and dosage of any drugs in this class.

Many of these medications raise serotonin levels. Combining them with Zofran can result in the rare but potentially dangerous serotonin syndrome. Some of the side effects listed below are signs of serotonin syndrome.

Zofran Side Effects

While taking Zofran for hangovers is generally safe, side effects are possible. Let your medical team know immediately if you are experiencing any of the following after using Zofran after drinking:

  • Breathing issues
  • Changes in heart rhythm
  • Chest pain
  • Chills
  • Confusion or irritability
  • Dizziness
  • Fever
  • Muscle spasms
  • Seizures
  • Unusual eye movements

A Holistic Alternative: IV Therapy

Ordinarily, Zofran is given either as a tablet that is swallowed or dissolved under the tongue. In its liquid formation, Zofran can also be added to an IV therapy solution.

IV therapy from Reset IV provides a holistic approach to hangover relief. The dehydration accompanying excessive drinking impacts virtually all hangover symptoms, from nausea to headache to fatigue. IV therapy offers rapid rehydration. It is far more effective than simply taking Zofran alone.

At Reset IV, we offer packages designed specifically for different types of hangover relief. Besides a saline solution for hydration, clients can choose packages containing anti-nausea, anti-heartburn, or pain relief medications. Customize your IV package with vitamins, minerals, and nutrients that can help you recover quickly.

Comparative Benefits of IV Therapy Over Zofran Alone

IV therapy is the best way to recover from a hangover. When taking Zofran for hangovers orally, you must wait for the medication to pass through your gastrointestinal tract. Taken orally, in the best-case scenario, Zofran starts working within 30 minutes. However, it can take up to two hours for its full effects to kick in. That’s a long time to keep suffering hangover symptoms, especially when vomiting is involved.

Since IV therapy enters your bloodstream immediately, Zofran’s effects are felt fast. While an IV therapy session usually lasts between 30 and 45 minutes, most clients report feeling better long before the session is over. Keep in mind that other than a slight pinch at the time of needle insertion, IV therapy is painless!

Making the Right Choice for Your Recovery

You want prompt relief when dealing with a serious hangover. You are likely not in a condition to drive to a doctor for treatment. Reset IV’s mobile IV therapy services are available 24/7 because you never know when you will need us. While we provide the same high-quality IV therapy you would receive in a hospital or doctor’s office, you don’t have to concern yourself with arranging transportation when battling a hangover.

At Reset IV, our licensed professional nurses should arrive at your home, hotel room or place of business within one hour of booking the appointment. They will answer any questions you have about IV therapy, Zofran for hangovers, and the medication, nutrients, and vitamins included in your particular package. 

Even better, there are no travel fees! Book your service now and pay later! 

IV therapy offers every element necessary for your recovery. While Zofran for hangovers stops nausea and vomiting, the saline solution delivers quick rehydration. Electrolytes assist in putting your system back in balance. Other add-ons of your choice address your individual symptoms. 

Getting Zofran for hangovers via IV therapy may be the right choice for your recovery! Feel better faster at Reset IV.